New polymer biomaterials are designed to trigger desired biological responses with the aim of resolving clinically relevant questions. Special emphasis is given to tissue regeneration and drug delivery where new materials are synthesized and evaluated in vitro and in vivo. The members of our group therefore have competences in organic and polymer synthesis, materials chemistry, biology and medicine allowing translation of basic molecular understanding to biological response in humans. Our current focus is on (i) biodegradable synthetic polymers that function as mechanical support or protection for regenerating tissues, (ii) soft materials/gels mimetic of the extracellular matrix designed to allow injection and (iii) materials that enables delivery across the cell membrane and to intracellular targets. Specific applications include regeneration of bone, cartilage, neural repair, soft tissue regeneration in urology and the treatment of diabetes.
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